During the Middle Ages, the nutmeg was a very expensive and valuable spice which was used as flavoring and medicine. In Elizabethan times, demand and its price increased, because of the plague that broke out in Europe. For many years, until the mid-19th century, the small island of Banda, in Indonesia, being the only producer of nutmeg, met many conquerors who wanted to gain the control of nutmeg’s production and trade. Nutmeg, when eaten in small quantities, does not cause any problem. But in large quantities, it can have psychoactive effects and cause poisoning. In cooking, nutmeg is used in very small quantities, otherwise it makes the food taste very bitter.